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. 2022 Jun 2;31(20):3458–3477. doi: 10.1093/hmg/ddac118

Figure 4.

Figure 4

Both vehicle and EH301 disease-associated modules have overlapping and unique GO functional annotations. (AC) Top 20 most significant non-redundant GO: BP terms (identified using the simplify function from the clusterProfiler package to merge terms with more than 40% overlapping annotated genes) enriched in the Greenyellow (A), Turquoise (B) and Salmon (C) modules from the vehicle network. (D) Venn diagram showing overlap of all significantly enriched GO terms in the Greenyellow, Turquoise and Salmon vehicle modules. (E, F) Top 20 most significant GO terms enriched in the Brown (E) and Red (F) modules from the EH301 network. (G) Venn Diagram showing overlap of all significantly enriched GO terms in the Brown, Red, Slateblue and Magenta4 EH301 modules.