Table 4.
iMN network modules with a significant trait association and GO annotation
| ALS | ALSFRS-R baseline | ALSFRS-R latest | ALSFRS-R progression | Age | Sex |
|---|---|---|---|---|---|
| Blue | Cyan | Magenta | Blue | Honeydew1 | Bisque4 |
| Magenta | Tan | Magenta | Darkgrey | ||
| Tan | Lightgreen | Tan | Bisque4 | ||
| Maroon | Yellowgreen | ||||
| Yellowgreen | Lightpink4 | ||||
| Cyan | Coral1 | ||||
| Lightpink4 | Darkred | ||||
| Darkgreen | Sienna3 | ||||
| Orangered4 | Black | ||||
| Lightyellow | Purple | ||||
| Turquoise |
sALS, sporadic amyotrophic lateral sclerosis; ALSFRS-R, revised ALS functional rating scale; DEGs, differentially expressed genes; FVC, forced vital capacity; GO, gene ontology; GSH, glutathione; iMN, induced motor neurons; NAD, nicotinamide adenine dinucleotide; NR, nicotinamide riboside; PT, pterostilbene; TF, transcription factor; WGCNA, weighted gene co-expression network analysis.