Table 1.
Baseline characteristics of the 31 ICA stenosis patients
| Characteristics | Overall(n = 31) | Moderate stenosis(> 50–69%)(n = 11) | Severe stenosis(≥ 70%)(n = 20) | P |
|---|---|---|---|---|
| Age, (median [IQR]) | 64.00 [58.50, 73.00] | 68.00 [65.50, 76.50] | 62.50 [52.75, 70.50] | 0.032 |
| Male, n(%) | 27 (87.1) | 10 (90.9) | 17 (85.0) | 0.639 |
| Vascular risk factors | ||||
| Hypertension, n(%) | 19 (61.3) | 8 (72.7) | 11 (55.0) | 0.452 |
| Diabetes mellitus, n(%) | 7 (22.6) | 4 (36.4) | 3 (15.0) | 0.21 |
| Hyperlipidemia, n(%) | 5 (16.1) | 2 (18.2) | 3 (15.0) | 0.818 |
| Coronary heart disease, n(%) | 3 (9.7) | 1 (9.1) | 2 (10.0) | 0.935 |
| Previous TIA, n(%) | 4 (12.9) | 3 (27.3) | 1 (5.0) | 0.115 |
| Previous stroke, n(%) | 9 (29.0) | 3 (27.3) | 6 (30.0) | 0.873 |
| Smoking, n(%) | 21 (67.7) | 8 (72.7) | 13 (65.0) | 0.660 |
| Drinking, n(%) | 16 (51.6) | 7 (63.6) | 9 (45.0) | 0.458 |
| CT perfusion parameters | ||||
| CBV, (median [IQR]) | 4.31 [3.59, 4.64] | 3.86 [3.25, 4.51] | 4.37 [3.94, 4.73] | 0.173 |
| rCBV, (median [IQR]) | 1.00 [0.95, 1.03] | 1.01 [0.98, 1.08] | 0.99 [0.92, 1.02] | 0.107 |
| CBF, (median [IQR]) | 43.29 [37.98, 48.13] | 47.55 [41.80, 53.41] | 40.78 [35.52, 46.79] | 0.029 |
| rCBF, (median [IQR]) | 1.08 [0.95, 1.21] | 1.05 [0.90, 1.11] | 1.16 [1.03, 1.28] | 0.099 |
| MTT, (median [IQR]) | 6.55 [5.69, 7.76] | 6.07 [5.32, 6.65] | 7.00 [5.96, 8.54] | 0.037 |
| rMTT, (median [IQR]) | 0.89 [0.85, 1.04] | 1.07 [0.96, 1.07] | 0.87 [0.76, 0.93] | 0.006 |
| TTP, (median [IQR]) | 20.90 [18.89, 21.81] | 19.33 [18.57, 20.41] | 21.53 [19.88, 21.92] | 0.063 |
| rTTP, (median [IQR]) | 0.98 [0.95, 1.00] | 1.00 [0.99, 1.02] | 0.96 [0.94, 0.98] | 0.001 |
| PS, (median [IQR]) | 14.38 [9.55, 16.67] | 11.51 [8.91, 16.27] | 14.52 [11.78, 16.93] | 0.457 |
| rPS, (median [IQR]) | 1.01 [0.91, 1.06] | 1.04 [0.95, 1.06] | 1.00 [0.87, 1.05] | 0.409 |
PS is expressed in mL·100 g−1·min−1; CBF in mL·min− 1·100 g− 1; CBV in mL·100 g− 1; and MTT and TTP are expressed in seconds
r relative, CBF cerebral blood flow, CBV cerebral blood volume, MTT mean transit time, TTP time to peak, PS permeability surface