Table 3. G6PD variants and allele frequency in 42 G6PD-deficient samples.
| G6PD variants | Male (228) | Female (292) | No. of X* Chr. | Total X or X* Chr. | Allele frequency | ||||
|---|---|---|---|---|---|---|---|---|---|
| Hemizygote (14) |
Normal (214) |
Homozygote (2) |
Heterozygote (26) |
Normal (264) |
|||||
| (X*Y) | (XY) | (X*X*) | X* | X | (XX) | ||||
| G6PD-Viangchan | 6 | 0 | 4 | 10 | 0 | 0 | 20 | 20 | 0.025 |
| G6PD-Mahidol | 4 | 0 | 0 | 6 | 0 | 0 | 10 | 10 | 0.012 |
| G6PD-Canton | 1 | 0 | 0 | 6 | 0 | 0 | 7 | 7 | 0.009 |
| G6PD-Union | 0 | 0 | 0 | 2 | 0 | 0 | 2 | 2 | 0.002 |
| G6PD-Vanua Lava | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0.001 |
| G6PD-Kaiping | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0.001 |
| G6PD-Uncharacterized | 2 | 0 | 0 | 1 | 0 | 0 | 3 | 3 | 0.004 |
| G6PD-Normal | 0 | 214 | 0 | 0 | 26 | 528 | 0 | 768 | 0.946 |
| Total | 14 | 214 | 4 | 26 | 26 | 528 | 44 | 812 | 1.000 |
Notes:
G6PD variants of all G6PD deficiency samples were calculated for allele frequency.
G6PD, Glucose-6-phosphate dehydrogenase.
X* represented the G6PD gene mutation.