. 2021 Nov 13;1(4):100075. doi: 10.1016/j.xops.2021.100075

Table 2.

Cognitive Impairment of Included Subjects versus Excluded Subjects

Diagnosis	Statistic	Included Subjects^†	Excluded Subjects^†	P^∗
Alzheimer disease	N (subjects,^∗ eyes)	35, 47	15, 20
Alzheimer disease	Mean MMSE (SD)	22.0 (4.8)	22.9 (4.7)	0.519
Mild cognitive impairment	N (subjects,^∗ eyes)	55, 85	21, 23
Mild cognitive impairment	Mean MMSE (SD)	26.9 (3.3)	26.6 (3.3)	0.684
Parkinson disease	N (subjects,^∗ eyes)	53, 87	20, 38
	Mean MMSE (SD)	28.8 (1.6)	27.8 (2.4)	0.043
	Mean Modified Hoehn and Yahr scale (SD)	2.04 (0.58)	2.15 (0.56)	0.053
Normal cognition	N (subjects,^∗ eyes)	92, 156	28, 39
Normal cognition	Mean MMSE (SD)	29.4 (1.3)	29.3 (1.3)	0.767

MMSE = Mini Mental State Examination (range, 0–30); SD = standard deviation. Boldface indicates statistical significance.

Modified Hoehn & Yahr Scale, describing the severity of Parkinson disease motor symptoms (range: 1 least involved to 4 most involved).

^∗

P value based on a Mann–Whitney U test for unequal means for MMSE and Modified Hoehn Yahr Scale.

^†

The sum of included subjects and excluded subjects, N, may not match the total number of subjects reported per diagnosis in Table 1, due to some subjects having 1 eye included and 1 eye excluded.