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. 2021 Mar 9;1(1):100006. doi: 10.1016/j.xops.2021.100006

Figure 3.

Figure 3

Increased cornea endothelial cell (CEC) migration speeds in Fuchs endothelial corneal dystrophy (FECD) ex vivo specimens compared with normal controls. A, Representative images of green fluorescent protein (GFP)-labeled CECs from high cell density (confluent) and low cell density (nonconfluent) areas on normal and FECD ex vivo specimens. Mean migration speed indicated by color maps. Scale bar = 100 μm. B, Bar graphs showing that nonconfluent normal and FECD CECs display increased mean speed compared with confluent CECs, nonconfluent FECD CECs display increased mean speed compared with normal CECs, nonconfluent normal and FECD CECs display increased mean maximum speed compared with confluent CECs, and nonconfluent and confluent FECD CECs display increased mean maximum speed compared with normal CECs. ∗∗∗P < 0.0001, 1-way analysis of variance, post hoc Bonferroni test. ns = nonsignificant; SEM = standard error of the mean.