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. 2021 Mar 9;1(1):100006. doi: 10.1016/j.xops.2021.100006

Figure 5.

Figure 5

Increased corneal endothelial cell (CEC) migration speeds in confluent conditions in Fuchs endothelial corneal dystrophy (FECD) compared with normal controls as detected by scratch assay. A, Representative phase contrast images at 0 hours, 8 hours, and 16 hours after a scratch on a monolayer of CECs from normal (HCEC-SV-67F-17) and FECD (FECD-SV-54F-73 and FECD-SV-74–22) sources. Scale bars = 100 μm. B, Line graph showing FECD CECs (FECD-SV-54F-73 and FECD-SV-74F-22) displaying increased cell migration speed compared with normal CECs (HCEC-SV-67F-17) as detected by closure of scratch area (n = 3). P < 0.0001, 2-way analysis of variance post hoc Bonferroni test. ∗P < 0.05. ∗∗P < 0.01. ∗∗∗P < 0.001. ns = nonsignificant; SD = standard deviation.