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. 2022 Sep 21;14(19):4575. doi: 10.3390/cancers14194575

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Flow cytometric analysis of conventional dendritic cell lineage I and II cells in melanoma (A,B) and lung cancer (C,D) demonstrated that response to therapy was tumor-dependent; in melanoma, there were significant differences among both populations based on treatment group whereas these differences were not observed in lung cancer (n = 3 per group). Significant differences are marked with a line with an asterisk. (Dendritic cells: CD3^–/CD19^–/CD11c⁺/MHCII⁺; conventional DC lineage I: CD3^–/CD19^–/CD11c⁺/MHCII⁺/XCR1⁺/CD11b^–/low, conventional DC lineage II: CD3^–/CD19^–/CD11c⁺/MHCII⁺/XCR1^–/CD11b⁺).