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. 2022 Sep 23;12:960509. doi: 10.3389/fonc.2022.960509

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Copyright © 2022 Lim-Fat, Macdonald, Lapointe, Climans, Cacciotti, Chahal, Perreault, Tsang, Gao, Yip, Keith, Bennett, Ramaswamy, Detsky, Tabori, Das and Hawkins

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Testing algorithm for adolescent and young adult high grade gliomas. HGG, high grade gliomas; AYA, adolescent and young adults; IDH, isocitrate dehydrogenase; ATRX, ATRX chromatin remodeler; CDKN, cyclin-dependent kinase inhibitor; FISH, fluorescence in situ hybridization; SNP, single nucleotide polymorphism; WHO, World Health Organization; DMG, diffuse midline glioma; EGFR, epidermal growth factor receptor; RNA, ribonucleic acid; EZHIP, EZH Inhibitory Protein; MMR, mismatch repair; cMMRD, constitutional mismatch repair deficiency; BRAF, B-Raf; MYCN, N-myc proto oncogene; RTK, receptor tyrosine kinase; NTRK, neurotrophic tyrosine receptor kinase; TERT, telomerase reverse transcriptase.