Table 1.
Model | Author | Sample/Method | Risk factor | Outcome | ||
---|---|---|---|---|---|---|
TAE for rHCC | Prediction of prognosis of TAE treatment of rHCC by imaging and clinical scoring systems | Ngan H et al | 33/Mantel-Cox test | Total bilirubin=2.9 mg/dl | mOS 1 week | |
Total bilirubin<2.9 mg/dl | mOS 15 weeks | |||||
Okazaki M et al | 38/Mantel-Cox test | Total bilirubin=3.0 mg/dl | mOS 13 days | |||
Total bilirubin ≤3.0 mg/dl | mOS 165 days | |||||
Lee KH et al | 111/Multiple logistic regression model | Bilobar tumor distribution(3points) | High risk≥4points | 30 days mortality 86.8% | ||
Total bilirubin=2.5mg/dL(2points) | Moderate risk=3points | 30 days mortality 31.8% | ||||
Albumin <30g/L(1points) | Low risk ≤ 2points | 30 days mortality 2.6% | ||||
Fan WZ et al | 94/Cox regression analysis | Shock index | ≥0.6=<1 | mOS 12.0 ± 1.0 days | ||
≥1 | mOS 52.0 ± 7.2 days | |||||
Child-Pugh score | 10/11 | mOS 51.0 ± 13.9 days | ||||
12/13 | mOS 28.0 ± 3.7 days | |||||
Portal vein tumor thrombus | Main | mOS 14.0 ± 2.0 days | ||||
Lobar | mOS 34.0 ± 5.1 days | |||||
Segmental | mOS 52.0 ± 6.9 days | |||||
MELD predicts TAE for rHCC | Jundt MC et al | 24/Log-rank test | MELD-Na score=16 | mOS 9 days, 30 days mortality 67% | ||
MELD-Na score ≤ 16 | mOS 166.5 days, 30 days mortality 21% | |||||
Partial liver resection for rHCC | TAA | Wu JJ et al | 139/Log-rank test | Scores according to the tumor size | High risk 10-13 points | 1 year OS 30.2% |
Scores according to the AFP | Moderate risk 6-9 points | 1 year OS 43.2% | ||||
Scores according to the ALP | Low risk 0-5 points | 1 year OS 88.1% | ||||
AFP | Chua DW et al | 79/Cox regression analysis | AFP=200 ng/mL | 1 year OS 33.3% | ||
Tumor size=10 cm | 1year recurrent rate 90.9% | |||||
She WH et al. | 114/Log-rank test | AFP≥256 ng/mL | mDFS 5.9 months | |||
AFP<256 ng/ml | mDFS 10.7 months |
TAE, transcatheter artery embolization; rHCC, ruptured hepatocellular carcinoma; MELD, Model for End-Stage Liver Disease; mOS, median overall survival; TAA, tumor-associated antigen; AFP, alpha-fetoprotein; mDFS, median disease-free survival.