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. 2022 Sep 29;12:973857. doi: 10.3389/fonc.2022.973857

Table 1.

The models of predicting the prognosis of rHCC.

Model Author Sample/Method Risk factor Outcome
TAE for rHCC Prediction of prognosis of TAE treatment of rHCC by imaging and clinical scoring systems Ngan H et al 33/Mantel-Cox test Total bilirubin=2.9 mg/dl mOS 1 week
Total bilirubin<2.9 mg/dl mOS 15 weeks
Okazaki M et al 38/Mantel-Cox test Total bilirubin=3.0 mg/dl mOS 13 days
Total bilirubin ≤3.0 mg/dl mOS 165 days
Lee KH et al 111/Multiple logistic regression model Bilobar tumor distribution(3points) High risk≥4points 30 days mortality 86.8%
Total bilirubin=2.5mg/dL(2points) Moderate risk=3points 30 days mortality 31.8%
Albumin <30g/L(1points) Low risk ≤ 2points 30 days mortality 2.6%
Fan WZ et al 94/Cox regression analysis Shock index ≥0.6=<1 mOS 12.0 ± 1.0 days
≥1 mOS 52.0 ± 7.2 days
Child-Pugh score 10/11 mOS 51.0 ± 13.9 days
12/13 mOS 28.0 ± 3.7 days
Portal vein tumor thrombus Main mOS 14.0 ± 2.0 days
Lobar mOS 34.0 ± 5.1 days
Segmental mOS 52.0 ± 6.9 days
MELD predicts TAE for rHCC Jundt MC et al 24/Log-rank test MELD-Na score=16 mOS 9 days, 30 days mortality 67%
MELD-Na score ≤ 16 mOS 166.5 days, 30 days mortality 21%
Partial liver resection for rHCC TAA Wu JJ et al 139/Log-rank test Scores according to the tumor size High risk 10-13 points 1 year OS 30.2%
Scores according to the AFP Moderate risk 6-9 points 1 year OS 43.2%
Scores according to the ALP Low risk 0-5 points 1 year OS 88.1%
AFP Chua DW et al 79/Cox regression analysis AFP=200 ng/mL 1 year OS 33.3%
Tumor size=10 cm 1year recurrent rate 90.9%
She WH et al. 114/Log-rank test AFP≥256 ng/mL mDFS 5.9 months
AFP<256 ng/ml mDFS 10.7 months

TAE, transcatheter artery embolization; rHCC, ruptured hepatocellular carcinoma; MELD, Model for End-Stage Liver Disease; mOS, median overall survival; TAA, tumor-associated antigen; AFP, alpha-fetoprotein; mDFS, median disease-free survival.