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. 2022 Sep 21;14(19):4572. doi: 10.3390/cancers14194572

Table 2.

Standardized mortality ratios for cardiovascular death in elderly patients with bladder cancer based on years after diagnosis.

Years After Diagnosis
<1 1–5 5–10 10–15 15+
Cause of Death Obs Smr
(95% CI)
Obs Smr
(95% CI)
Obs Smr
(95% CI)
Obs Smr
(95% CI)
Obs Smr
(95% CI)
65+ years
CVD 2686 1.57 7207 1.23 5805 1.28 3244 1.3 2270 1.34
(1.51–1.63) (1.20–1.26) (1.25–1.32) (1.25–1.34) (1.28–1.39)
Diseases of the Heart 2124 1.62 5615 1.25 4483 1.29 2472 1.29 1704 1.32
(1.55–1.69) (1.21–1.28) (1.25–1.33) (1.24–1.35) (1.25–1.38)
Cerebrovascular Diseases 380 1.34 1075 1.1 906 1.19 523 1.22 387 1.33
(1.21–1.48) (1.04–1.17) (1.11–1.27) (1.12–1.33) (1.20–1.46)
Hypertension without Heart Disease 40 1.4 104 1 113 1.25 81 1.41 86 1.82
(1.00–1.90) (0.82–1.21) (1.03–1.50) (1.12–1.76) (1.46–2.25)
Atherosclerosis 67 1.83 161 1.34 123 1.42 74 1.68 40 1.46
(1.42–2.32) (1.14–1.56) (1.18–1.69) (1.32–2.11) (1.05–1.99)
Aortic Aneurysm and Dissection 46 1.55 172 1.72 123 1.71 53 1.49 29 1.47
(1.14–2.07) (1.48–2.00) (1.42–2.04) (1.12–1.95) (0.99–2.12)
Other Diseases of the Arteries, Arterioles, and Capillaries 29 1.78 80 1.44 57 1.3 41 1.64 24 1.38
(1.19–2.56) (1.14–1.79) (0.99–1.69) (1.17–2.22) (0.89–2.06)
65–74 years
CVD 632 1.94 2073 1.51 2090 1.4 1628 1.19 1690 1.18
(1.79–2.10) (1.45–1.58) (1.34–1.46) (1.13–1.25) (1.12–1.24)
Diseases of the Heart 506 1.92 1637 1.5 1652 1.42 1230 1.17 1259 1.15
(1.76–2.10) (1.43–1.57) (1.35–1.49) (1.11–1.24) (1.09–1.21)
Cerebrovascular Diseases 87 2.01 286 1.47 297 1.25 276 1.19 298 1.21
(1.61–2.48) (1.30–1.65) (1.11–1.40) (1.05–1.34) (1.08–1.36)
Hypertension without Heart Disease 6 1.4 23 1.19 32 1.3 43 1.48 62 1.56
(0.52–3.06) (0.76–1.79) (0.89–1.84) (1.07–2.00) (1.20–2.00)
Atherosclerosis 11 2.97 34 2.01 32 1.57 23 1.06 27 1.19
(1.48–5.32) (1.39–2.80) (1.07–2.22) (0.67–1.59) (0.78–1.73)
Aortic Aneurysm and Dissection 10 1.22 69 2.04 64 1.92 35 1.52 24 1.41
(0.59–2.25) (1.58–2.58) (1.48–2.45) (1.06–2.11) (0.91–2.10)
Other Diseases of the Arteries, Arterioles, and Capillaries 12 3.6 24 1.71 13 0.85 21 1.5 20 1.36
(1.86–6.30) (1.10–2.55) (0.45–1.45) (0.93–2.29) (0.83–2.11)
75–84 years
CVD 1140 1.59 3179 1.08 2733 1.07 1426 1.33 560 2.16
(1.50–1.69) (1.04–1.12) (1.03–1.11) (1.27–1.41) (1.98–2.35)
Diseases of the Heart 894 1.63 2462 1.1 2077 1.07 1089 1.34 429 2.18
(1.53–1.74) (1.05–1.14) (1.02–1.12) (1.26–1.42) (1.98–2.40)
Cerebrovascular Diseases 169 1.37 502 0.99 462 1.05 223 1.21 86 1.88
(1.17–1.60) (0.91–1.08) (0.96–1.16) (1.06–1.38) (1.51–2.33)
Hypertension without Heart Disease 18 1.62 40 0.76 61 1.12 36 1.35 24 3.25
(0.96–2.57) (0.55–1.04) (0.85–1.43) (0.94–1.87) (2.08–4.84)
Atherosclerosis 23 1.67 67 1.08 56 1.02 44 2.08 12 2.66
(1.06–2.51) (0.83–1.37) (0.77–1.33) (1.51–2.80) (1.38–4.65)
Aortic Aneurysm and Dissection 24 1.71 70 1.44 47 1.42 15 1.27 5 1.88
(1.10–2.55) (1.12–1.81) (1.04–1.88) (0.71–2.09) (0.61–4.39)
Other Diseases of the Arteries, Arterioles, and Capillaries 12 1.75 38 1.38 30 1.26 19 1.82 4 1.52
(0.90–3.05) (0.98–1.90) (0.85–1.80) (1.09–2.84) (0.41–3.89)
85+ years
CVD 914 1.38 1955 1.27 982 2.01 190 3.04 20 4.39
(1.29–1.47) (1.21–1.33) (1.89–2.14) (2.63–3.51) (2.68–6.78)
Diseases of the Heart 724 1.45 1516 1.3 754 2.04 153 3.24 16 4.67
(1.34–1.56) (1.24–1.37) (1.89–2.19) (2.75–3.80) (2.67–7.59)
Cerebrovascular Diseases 124 1.05 287 1.06 147 1.72 24 2.17 3 3.63
(0.87–1.25) (0.94–1.19) (1.45–2.02) (1.39–3.23) (0.75–10.61)
Hypertension without Heart Disease 16 1.21 41 1.27 20 1.78 2 1.24 0 -
(0.69–1.96) (0.91–1.72) (1.09–2.75) (0.15–4.49) -
Atherosclerosis 33 1.72 60 1.45 35 3.01 7 5.45 1 12.9
(1.19–2.42) (1.11–1.87) (2.10–4.19) (2.19–11.23) (0.33–71.88)
Aortic Aneurysm and Dissection 12 1.62 33 1.92 12 2.28 3 4.63 0 -
(0.84–2.83) (1.32–2.70) (1.18–3.98) (0.96–13.53)
Other Diseases of the Arteries, Arterioles, and Capillaries 5 0.83 18 1.28 14 3.09 1 1.63 0 -
(0.27–1.93) (0.76–2.03) (1.69–5.18) (0.04–9.07) -

Abbreviations: CVD, cardiovascular disease; CI, confidence interval; Obs, observed; SMR, standardized mortality ratio.