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. 2022 Apr 21;65(5):1867–1893. doi: 10.1044/2022_JSLHR-21-00575

Table 4.

Sensorimotor mechanisms: subcategories, characteristics, and triggers.

Author(s), year Subcategories Associated characteristics Potential triggers
Dworkin et al. (2000); McKenna et al. (2020); Nagy et al. (2020); Schultz-Coulon (1978); Stepp et al., (2017); Ziethe et al. (2019) Disrupted sensorimotor integration/control Abnormal response to pitch shifting and masking experiments
Shorter voice onset time and greater coefficient of variation of voice onset time
Reduced auditory discrimination abilities
Potential hearing impairment
Disruptions in voice production pattern (e.g., URI; high voice-use), psychological factors (e.g., emotional stress), poor vocal quality
Kryshtopava et al. (2017); Urberg-Carlson (2013)
Theory of neural models/adaptive learning

Neurological signs of altered sensorimotor control of phonation: reduced brain activity in sensory control-related areas; increased brain activity in motor control-related areas

Poor vocal quality, organic pathology (resolved), disrupted proprioceptive feedback, URI, stress, vocal demands

Morrison et al. (1999); Vertigan et al. (2006, 2008, 2013, 2014)

Irritable larynx syndrome/
laryngeal sensory dysfunction/ laryngeal hypersensitivity syndrome

Signs of extrathoracic hyperresponsiveness (coughing, throat clearing)
Increased cough reflex sensitivity
Episodic laryngospasms
Possible associated symptom: globus pharyngeus
Abnormal response to methacholine or hypertonic saline challenge
Cross-stimulus responses (a domain-specific stimulus causing a response in a different domain)

Viral infection (including URI), Environmental stimuli (e.g., odor, chemicals, cold air), allergies, emotional distress, postural behavior, GERD/LPR, tissue injury, voice use, cough, foods/esophageal irritants, exertion, respiratory diseases (e.g., asthma), immune disorder

Note. URI = upper respiratory tract infection; GERD = gastroesophageal reflux disease; LPR = laryngopharyngeal reflux.