TABLE 4.
Antibacterial activity of spiropyridoindolepyrrolidines 7a-7g.
| Compound | Staphylococcus aureus (+) | Bacillus cereus (+) | Escherichia coli (-) | Klebsiella pneumoniae (-) |
|---|---|---|---|---|
| 7a | 9 | 11 | 10 | 8 |
| 7b | 18 | 21 | 22 | 19 |
| 7c | 17 | 21 | 22 | 18 |
| 7d | 10 | 7 | 11 | 8 |
| 7e | 17 | 19 | 20 | 22 |
| 7f | 10 | 9 | 11 | 12 |
| 7g | 19 | 23 | 24 | 22 |
| Streptomycin | 18 | 24 | 25 | 23 |
| Gentamicin | 21 | 23 | 24 | 21 |
Bold indicates best condition for performing reactions.