Table 3.
Univariate and Multivariate Cox Regression Analysis of TIMM8A and Clinical Data.
| Characteristics | Total(N) | HR(95% CI) Univariate analysis | P value Univariate analysis | Characteristics | Total(N) | HR(95% CI) Multivariate analysis | P value Multivariate analysis | ||
|---|---|---|---|---|---|---|---|---|---|
| T stage | 1079 |
|
T stage | 1079 |
|
||||
| T1&T2 | 905 | Reference | T1&T2 | 905 | |||||
| T3&T4 | 174 | 1.608 (1.110-2.329) | 0.012 | T3&T4 | 174 | 2.66 (1.469-4.834) | 0.001 | ||
| N stage | 1063 | N stage | 1063 | ||||||
| N0&N1 | 871 | Reference | N0&N1 | 871 | |||||
| N2&N3 | 192 | 2.163 (1.472-3.180) | <0.001 | N2&N3 | 192 | 1.960 (1.092-3.520) | 0.024 | ||
| M stage | 922 | M stage | 922 | ||||||
| M0 | 902 | Reference | M0 | 902 | |||||
| M1 | 20 | 4.254 (2.468-7.334) | <0.001 | M1 | 20 | 4.492 (1.872-10.776) | <0.001 | ||
| Age | 1082 | Age | 1082 | ||||||
| <=60 | 601 | Reference | <=60 | 601 | |||||
| >60 | 481 | 2.020 (1.465-2.784) | <0.001 | >60 | 481 | 2.892 (1.773-4.717) | <0.001 | ||
| PR status | 1029 | PR status | 1029 | ||||||
| Negative | 342 | Reference | Negative | 342 | |||||
| Positive | 687 | 0.732 (0.523-1.024) | 0.068 | Positive | 687 | 1.122 (0.520-2.422) | 0.77 | ||
| ER status | 1032 | ER status | 1032 | ||||||
| Negative | 240 | Reference | Negative | 240 | |||||
| Positive | 792 | 0.712 (0.495-1.023) | 0.066 | Positive | 792 | 0.505 (0.224-1.135) | 0.98 | ||
| HER2 status | 715 | HER2 status | 715 | ||||||
| Negative | 558 | Reference | Negative | 558 | |||||
| Positive | 157 | 1.593 (0.973-2.609) | 0.064 | Positive | 157 | 1.215 (0.698-2.117) | 0.491 | ||
| TMM8A | 1082 | 1.438 (1.22-1.844) | 0.004 | TMM8A | 1082 | 1.688 (1.100-2.588) | 0.016 | ||
| 2 4 6 | 0 3 69 |