Table 1.
Baseline Demographics for Each Genotype Group
| Group A (n = 24) | Group B (n = 21) | Group C (n = 24) | P Value∗ | |
|---|---|---|---|---|
| Age at symptom onset (yrs) | 8.9 ± 1.9 | 20.3 ± 14.5 | 44.8 ± 25.6 | < 0.001 |
| Age at baseline assessment (yrs) | 28.5 ± 16.1 | 40.6 ± 13.8 | 53.2 ± 20.7 | < 0.001 |
| Disease duration (yrs) | 19.6 ± 16.0 | 20.5 ± 13.9 | 9.2 ± 8.9 | 0.008 |
| Baseline VA right eye (ETDRS letters) | 18 ± 23 | 37 ± 28 | 59 ± 20 | < 0.001 |
| Baseline DDAF area in right eye (mm2) | 73 ±152 | 18 ± 25 | 2.9 ± 5.1 | 0.024 |
| Baseline DDAF square-root-area in right eye (mm) | 5.6 ± 6.6 | 3.5 ± 2.6 | 1.2 ± 1.2 | 0.003 |
| Patients with follow-up data | 16 (67) | 20 (95) | 15 (63) | N/A |
DDAF = definitely decreased autofluorescence; ETDRS = Early Treatment Diabetic Retinopathy Study; N/A = not applicable; VA = visual acuity.
Data are presented as mean±standard deviation or no. (%).
∗
One-way analysis of variance.