TABLE 1.

Specificities and sensitivities of various individual proteins and combinations of homolous proteins in IgG WB

Categorya	Antigen	Strain	Specificity (%)b	Sensitivity (%)c
I	p83/100	PKa2	100.0	28.0
	p83/100	PKo	100.0	27.5
	p83/100	PBi	99.3	32.8
	p83/100	All 3 strainsd	99.3	34.4
	p58	PKa2	99.3	37.0
	p58	PKo	97.2	46.6
	p58	PBi	99.3	34.4
	p58	All 3 strainsd	97.2	50.3
	p39	PKa2	97.9	16.9
	p39	PKo	98.6	37.6
	p39	PBi	100.0	35.4
	p39	All 3 strainsd	96.5	40.7
	p30	PKa2	96.5	27.5
	p30	PKo	99.3	24.9
	p30	PBi	97.9	28.6
	p30	All 3 strainsd	95.7	33.3
	OspC	PKa2	97.2	14.3
	OspC	PKo	99.3	14.3
	OspC	PBi	97.9	20.6
	OspC	All 3 strainsd	94.3	30.7
	p21	PKa2	100.0	25.4
	p21	PKo	100.0	23.3
	p21	PBi	100.0	28.6
	p21	All 3 strainsd	100.0	30.7
II	p75	PKa2	90.1	24.9
	p75	PKo	92.2	19.0
	p75	PBi	88.7	27.0
	p66	PKa2	100.0	11.1
	p66	PKo	95.7	7.4
	p66	PBi	97.9	8.5
	p60	PKa2	92.2	21.2
	p60	PKo	95.7	5.8
	p60	PBi	90.8	23.3
	p41	PKa2	64.5	53.4
	p41	PKo	78.7	45.5
	p41	PBi	65.2	56.6
	OspA	PKa2	99.3	0.5
	OspA	PKo	97.9	2.1
	OspA	PBi	95.7	4.8
III	p56	PKa2	100.0	29.6
	p43	PKo	93.6	38.6
	p35	PKo	97.2	12.7
	p17a	PKa2	100.0	13.2
	p17	PKo	96.5	40.7
	p17b	PBi	99.3	15.9
	p14	PKo	99.3	29.6

^aCategory I, highly specific antigens with sensitivities of >14%; homologs of all three strains known. II, well-known antigens with low specificity and/or low sensitivity; homologs of all three strains known. III, antigens identified in only one strain; interesting as additional diagnostic antigens. 

^bSpecificities were determined with the data of 141 sera of the control group. 

^cSensitivities were determined with the data of 189 sera from patients at different stages of LB. 

^dA positive result in the combination means that at least one of the antigens was reactive.