Table 6.
Number of Anti-VEGF in the First 12 Mos | Cases (No./%) | Average Number of Anti-VEGF Injections within the Specified Period (±SD) |
||||||||
---|---|---|---|---|---|---|---|---|---|---|
Accumulative |
By the Year |
|||||||||
0–24 mos | 0–36 mos | 0–48 mos | 0–60 mos | 13–24 mos | 25–36 mos | 37–48 mos | 49–60 mos | |||
1 | 35 108 | 18.7 | 1.26 ± 0.85 | 1.55 ± 1.62 | 1.91 ± 2.49 | 2.41 ± 3.60 | 0.26 ± 0.85 | 0.29 ± 0.99 | 0.33 ± 1.09 | 0.38 ± 1.22 |
2 | 25 473 | 13.6 | 2.52 ± 1.14 | 3.05 ± 2.14 | 3.62 ± 3.27 | 4.34 ± 4.59 | 0.52 ± 1.14 | 0.52 ± 1.28 | 0.54 ± 1.39 | 0.59 ± 1.55 |
3 | 50 136 | 26.8 | 3.65 ± 1.31 | 4.33 ± 2.47 | 5.02 ± 3.66 | 5.76 ± 4.93 | 0.65 ± 1.31 | 0.68 ± 1.50 | 0.69 ± 1.58 | 0.73 ± 1.68 |
4 | 23 073 | 12.3 | 5.41 ± 1.76 | 6.67 ± 3.25 | 7.88 ± 4.77 | 9.14 ± 6.37 | 1.41 ± 1.76 | 1.24 ± 1.87 | 1.16 ± 1.95 | 1.19 ± 2.11 |
5 | 16 306 | 8.7 | 7.09 ± 2.08 | 8.87 ± 3.88 | 10.56 ± 5.66 | 12.25 ± 7.49 | 2.09 ± 2.08 | 1.77 ± 2.21 | 1.63 ± 2.29 | 1.60 ± 2.41 |
6 | 14 665 | 7.8 | 8.53 ± 2.27 | 10.66 ± 4.27 | 12.58 ± 6.30 | 14.48 ± 8.39 | 2.53 ± 2.27 | 2.12 ± 2.46 | 1.95 ± 2.55 | 1.87 ± 2.63 |
7 | 10 693 | 5.7 | 10.5 ± 2.47 | 13.4 ± 4.83 | 16.00 ± 7.16 | 18.82 ± 9.63 | 3.50 ± 2.47 | 2.89 ± 2.80 | 2.65 ± 2.85 | 2.57 ± 3.00 |
8 | 5730 | 3.1 | 12.3 ± 2.71 | 15.92 ± 5.31 | 18.98 ± 7.89 | 21.87 ± 10.45 | 4.31 ± 2.71 | 3.57 ± 3.07 | 3.10 ± 3.19 | 2.99 ± 3.29 |
9 | 2983 | 1.6 | 14.0 ± 3.01 | 18.21 ± 3.04 | 21.35 ± 7.81 | 24.38 ± 11.85 | 5.01 ± 3.01 | 4.14 ± 3.57 | 3.47 ± 3.47 | 3.31 ± 3.65 |
10 | 1655 | 0.9 | 15.86 ± 3.25 | 20.41 ± 6.26 | 24.64 ± 9.44 | 28.47 ± 12.45 | 5.86 ± 3.25 | 4.71 ± 3.63 | 4.27 ± 3.89 | 4.00 ± 3.78 |
11 | 976 | 0.5 | 17.84 ± 3.51 | 23.29 ± 6.82 | 27.48 ± 10.05 | 31.72 ± 13.92 | 6.84 ± 3.51 | 5.53 ± 3.90 | 4.70 ± 4.15 | 4.22 ± 4.29 |
12 | 621 | 0.3 | 19.6 ± 3.80 | 25.22 ± 7.83 | 29.79 ± 11.92 | 33.68 ± 14.28 | 7.58 ± 3.80 | 5.72 ± 4.61 | 4.82 ± 4.70 | 4.09 ± 4.19 |
SD = standard deviation; VEGF = vascular endothelial growth factor.
The first 12 months refer to the 12 months from each initial treatment.
Injection numbers are presented as mean ± standard deviation.