Table 7.

Local Adverse Events After Initial Anti-VEGF Injection for Age-related Macular Degeneration

Adverse Event	Duration After Initial Treatment	Incident Cases			Incident Proportion
		Men	Women	Total	Total
Endophthalmitis	In 1 yr	81	51	132	0.054%
	In 2 yrs	105	65	170	0.069%
	In 3 yrs	122	78	200	0.081%
Retinal detachment	In 1 yr	326	142	468	0.19%
	In 2 yrs	460	198	658	0.26%
	In 3 yrs	549	229	778	0.32%

VEGF = vascular endothelial growth factor.

Endophthalmitis and retinal detachment were defined on the basis of diagnosis codes and pars plana vitrectomy (PVV).

Incident proportions were calculated by dividing the number of incident cases by the number of patients who received anti-VEGF injections as the initial treatment for AMD (n = 246 064).