Figure 4. Estimated Simple Slopes for Change in GCIPL Thickness (A and B) and cGMV (C and D) Given Interactions With Disease Duration or Cumulative Number of Relapses.

Point estimates with 95% CIs are shown, along with symbols to delineate statistically significative differences in pairwise contrasts between patients who were younger than 35 at the first visit and other age categories. p Values corrected for multiple comparisons with the Tukey method. cGMV = cortical gray matter volume; GCIPL = ganglion cell-inner plexiform layer.