Figure 1. Kaplan-Meier Plots Showing the Relationship Between Baseline Levels of CSF t-tau, ptau181, and the Ratio Aβ42/Aβ40 and Time to Onset of Clinical Symptoms of MCI.

Higher levels of CSF t-tau (A) and ptau181 (B) and lower levels of Aβ42/Aβ40 (C) are significantly associated with a shorter time to onset of clinical symptoms of MCI among individuals who were cognitively normal at baseline. MCI = mild cognitive impairment; t-tau = total tau.