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| Inclusion criteria |
|---|
| Female |
| Age of onset (<35y) |
| BMI ≤40 kg/m2 |
| Waist-hip ratio (WHR) ≤0.85 |
| No or minimal central (android) obesity |
| Bilateral and symmetrical fat hypertrophy on lower limbs |
| Spared feet |
| Persistent enlargement (with no significant effect from overnight elevation) |
| White British ethnicity (only for the GWAS) |
