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. 2022 Feb 4;2(2):100123. doi: 10.1016/j.xops.2022.100123

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© 2022 by the American Academy of Ophthalmology.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Pearson correlation coefficient matrix showing the association between the cytokine levels and the ultra-widefield fluorescein angiography (UWFA) features identified by (A) bicluster 1 and (B) bicluster 2, respectively, and (C) the texture-based OCT features identified by bicluster 3. Strong association between vascular endothelial growth factor (VEGF) and leakage shape and vessel tortuosity-based UWFA features and between VEGF and texture-based OCT features are observed. ∗Statistically significant (P < 0.05) relationship. ANGPTL4 = angiopoietin-like 4; HGF = hepatocyte growth factor; IL = interleukin; IRF = intraretinal fluid; Max = maximum; MCP-1 = monocyte chemoattractant protein 1; Min = minimum; MST = minimum spanning tree; SRF = subretinal fluid; TIMP = tissue inhibitor of metalloproteinase; UPAR = urokinase plasminogen activator receptor.