Table 3.
Multivariate Regression Analyses for Assessment of Quality of Life 8-Dimension Utility Values
| Variable | Base Model (Model 1) |
Extended Model (Model 2), Mental Health Conditions |
Extended Model (Model 3), Mental Health Conditions, Age, Gender, Diagnosis, Age at Diagnosis |
Base Model (Model 4) 25-Item National Eye Institute Visual Function Questionnaire |
Extended Model (Model 5), 25-Item National Eye Institute Visual Function Questionnaire Mental Health Conditions |
Extended Model (Model 6), 25-Item National Eye Institute Visual Function Questionnaire Mental Health Conditions, Age, Gender, Diagnosis, Age at Diagnosis |
||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Coefficient | 95% Confidence Interval | Coefficient | 95% Confidence Interval | Coefficient | 95% Confidence Interval | Coefficient | 95% Confidence Interval | Coefficient | 95% Confidence Interval | Coefficient | 95% Confidence Interval | |
| NEI-VFQ-39 score | 0.0084∗ | 0.007–0.010 | 0.007∗ | 0.006–0.009 | 0.007∗ | 0.005–0.009 | ||||||
| NEI-VFQ-25 score | 0.0082∗ | 0.006–0.010 | 0.0069∗ | 0.005–0.009 | 0.0064∗ | 0.004–0.009 | ||||||
| Mental health condition (yes =1) | –0.144∗ | –0.197 to –0.090 | –0.145∗ | –0.204 to –0.086 | –0.150∗ | –0.206 to –0.093 | –0.154∗ | –0.216 to –0.092 | ||||
| Gender (male = 1) | –0.005 | –0.062 to 0.052 | –0.016 | –0.074 to 0.043 | ||||||||
| Age | 0.001 | –0.001 to 0.003 | 0.001 | –0.002 to 0.003 | ||||||||
| Age at awareness of diagnosis (yrs) | ||||||||||||
| 19–30 | 0.001 | –0.084 to 0.087 | –0.0002 | –0.091 to 0.091 | ||||||||
| 31–45 | –0.028 | –0.118 to 0.062 | –0.023 | –0.117 to 0.072 | ||||||||
| >45 | –0.028 | –0.148 to 0.091 | –0.009 | –0.136 to 0.118 | ||||||||
| Visual acuity | 0.026 | –0.048 to 0.099 | 0.048 | –0.026 to 0.123 | ||||||||
| Normal/mild/moderate (≥20/200) | ||||||||||||
| Profound severe (≤20/200), reference | ||||||||||||
| Intercept | 0.168∗ | 0.081–0.256 | 0.308∗ | 0.218–0.398 | 0.298∗ | 0.168 – 0.427 | 0.189∗ | 0.098–0.280 | 0.332 | 0.238–0.427 | 0.321∗ | 0.184–0.457 |
| No. | 70 | 70 | 70 | 70 | 70 | 70 | ||||||
| R2 value | 0.596 | 0.717 | 0.730 | 0.550 | 0.682 | 0.688 | ||||||
NEI-VFQ-25 = 25-item National Eye Institute Visual Functioning Questionnaire; NEI-VFQ-39 = 39-item National Eye Institute Visual Functioning Questionnaire.
Dependent variable AQoL-8D utility values are presented.
∗
P < 0.001.