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. 2022 Sep 29;13:956378. doi: 10.3389/fmicb.2022.956378

Figure 1.

Figure 1

Biotransformation of natural products by key gut microbes. (A) β-glucuronidase of E. coli HGU-3 catalyzes hydrolysis of baicalin to yield baicalein (Han et al., 2016; Li D. et al., 2019). (B) Feruloyl esterases from B. animalis, L. reuteri, L. helveticus, and L. fermentum catalyzes hydrolysis of chlorogenic acid into caffeic acid (Raimondi et al., 2015; Pang et al., 2016; Aguirre Santos et al., 2018). (C) β-glucosidase of Eubacterium L-8 and Streptococcus LJ-22 catalyzes hydrolysis of glycyrrhizin to 18β-glycyrrhetinic acid (Kim et al., 1999; Chen B. et al., 2021). (D) α-L-rhamnosidase from Bacteroides sp. 45 catalyzes hydrolysis of rutin to quercetin 3-O-glucoside (Riva et al., 2020). (E) O-Methyltransferase from Blautia sp. MRG-PMF1 catalyzes the demethylation of curcumin to demethoxycurcumin (Burapan et al., 2017a,b). Created with BioRender.com.