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. Author manuscript; available in PMC: 2023 Oct 1.
Published in final edited form as: J Pain. 2022 Jun 10;23(10):1724–1736. doi: 10.1016/j.jpain.2022.05.008

Table 2.

Unadjusted means and 95% confidence limits (CL) of circulating concentrations (ng/mL) of omega-3 (n-6) and omega-6 (n-3) essential fatty acids and long-chain polyunsaturated fatty acids in erythrocyte membranes, stratified by TMD and low back pain case status

Painful TMD non-case (n=333) Painful TMD case (n=170)
Mean 95% CL Mean 95% CL P
Linoleic acid 18:2n-6 1088.6 979.1, 1198.0 1172.5 1019.3, 1325.7 0.381
α-linolenic acid 18:3n-3 77.1 70.0, 84.1 81.4 71.6, 91.3 0.478
Arachidonic acid 20:4n-6 76.6 69.9, 83.4 83.9 74.5, 93.3 0.219
Eicosapentaenoic acid 20:5n-3 101.5 90.2, 112.8 95.1 79.3, 111.0 0.520
Docosahexaenoic acid 22:6n-3 19.2 17.0, 21.3 17.9 14.9, 20.9 0.493
n-6/n-3 PUFA ratio (×100) 86.8 81.3, 92.3 99.9 92.2, 107.6 0.007
Low back pain non-case (n=381) Low back pain case (n=122)
Mean 95% CL Mean 95% CL P
Linoleic acid 18:2n-6 1140.2 1037.9, 1242.5 1044.3 863.5, 1225.1 0.365
α-linolenic acid 18:3n-3 79.3 72.8, 85.9 76.1 64.5, 87.7 0.634
Arachidonic acid 20:4n-6 76.5 70.2, 82.8 87.2 76.1, 98.4 0.099
Eicosapentaenoic acid 20:5n-3 99.8 89.2, 110.4 98.0 79.3, 116.7 0.872
Docosahexaenoic acid 22:6n-3 19.7 17.7, 21.7 15.6 12.1, 19.1 0.043
n-6/n-3 PUFA ratio (×100) 87.9 82.8, 93.1 101.4 92.4, 110.5 0.011