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. 2022 Oct 13;13:6062. doi: 10.1038/s41467-022-33840-6

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a Primary and b secondary conjugated and unconjugated bile acids in serum from male and female mice following chronic sucrose intake show sexual dimorphism as determined by two-way ANOVA with post hoc Tukey’s test (or Scheirer–Ray–Hare test and post-hoc Wilcoxon Rank Sum test with continuity correction for DCA, which demonstrated a non-parametric distribution). TαMCA/TβMCA: combined tauro-α-muricholic acid/tauro-β-muricholic acid (MC: n = 8, MS: n = 9, FC: n = 10, FS: n = 9), TωMCA: tauro-ω-mecholic acid (MC: n = 8, MS: n = 9, FC: n = 10, FS: n = 9), TCA taurocholic acid (MC: n = 8, MS: n = 9, FC: n = 10, FS: n = 9), CA cholic acid (MC: n = 8, MS: n = 9, FC: n = 10, FS: n = 9), αMCA α-muricholic acid (MC: n = 3, MS: n = 5, FC: n = 6, FS: n = 8), βMCA: β-muricholic acid (MC: n = 6, MS: n = 6, FC: n = 10, FS: n = 8), TDCA: tauro-deoxycholic acid (MC: n = 8, MS: n = 9, FC: n = 10, FS: n = 9), TUDCA/THDCA: combined tauro-ursodeoxycholic acid/tauro-hyodeoxycholic acid (MC: n = 8, MS: n = 9, FC: n = 9, FS: n = 9), UDCA: ursodeoxycholic acid (MC: n = 1, MS: n = 0, FC: n = 10, FS: n = 9), DCA deoxycholic acid (MC: n = 8, MS: n = 9, FC: n = 9 FS: n = 9). Data displayed are the group means ± standard error with biologically independent values overlayed (see figure for p-values). Source data are provided in the source data file.