Table 2.
Histological changes | Control | MTX | MF 10 | MF 20 | MF 40 | MF 20 + BADGE |
---|---|---|---|---|---|---|
Damaged glomeruli | − | +++ | ++ | + | + | +++ |
Luminal casts | − | ++ | − | − | − | ++ |
Disorganized tubules | − | +++ | + | + | + | +++ |
Extravasated haemorrhage | − | ++ | + | − | − | ++ |
Histopathological scores were designed as follows: (−, negative; +, weak; ++, moderate; +++, severe).