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. 2022 Sep 30;9:1004508. doi: 10.3389/fcvm.2022.1004508

TABLE 1.

Overview of studies reporting reference values for blood pressure during exercise testing in childhood.

Author Age N (m/f) Country Selection Device Protocol Termination Normalization Adjustment Limitations
Clarke et al., 2021 (31) 6–18 y 648 (314/334) Australia Single center routine examination, normal cardiac anatomy, BMI < P95, BP < P95 Treadmill Bruce protocol Exhaustion P5, P10, P50, P90, P95 of SBP change Age, sex, height Reports only change of SBP from baseline
Sasaki et al., 2021 (34) 7–17 y 1085 (642/397) USA Single center routine examination, normal cardiac anatomy Treadmill Modified Bruce protocol Exhaustion Table for P5, P10, P50, P90, P95 of SBP/DBP
Formula by linear regression for P50, P90, P95 of SBP
Age, sex No adjustment for height
Burstein et al., 2021 (59) 6–18 y 1829 (951/878) USA Single center routine examination, BMI P5-P95, normal cardiac anatomy Cycle Ramp (10–25 W/min) Exhaustion Trajectories and formula (fractional polynomial regression) Age, sex, BMI, race Not readily usable in practice
Szmigielska et al., 2016 (32) 10–18 y 711 (457/254) Poland Athletes, single center, resting BP < P90 Cycle Individual (multi stage 30/60 W every 3 min) Exhaustion Diagram (multivariate linear regression) depicting 2 SEE Age, sex, workload No adjustment for height
Hacke and Weisser, 2016 (33) 12–17 y 492 (251/241) Germany 6 public schools no diagnosis of hypertension or CV disease Cycle Individual (multi-stage 0.5 W/kg every 3 min) Submaximal 1.5 W/kg P95 and P90 of SBP Age, sex No adjustment for height
Wanne and Haapoja, 1988 (60) 9–18 y 497 (260/237) Finland Random sample from multi-center study (n = 14.487) corrected for age and social class Cycle Ramp (HR controlled, increment of 8 bpm) HR of 170 bpm Trajectories with 2SD adjusted Sex, HR, puberty
(9–12 y/14–18 y)
Age group 12–14 y not reported

BMI, body mass index; bpm, beats per minute; CV, cardiovascular; DBP, diastolic blood pressure; f, female; HR, heart rate; m, male; N, number; P, percentile; SBP, systolic blood pressure; SD, standard deviation; SEE, standard error of estimate; W, watt; y, years.