Table 3.
Clinical parameters of the study population
| Group | ||||
|---|---|---|---|---|
| Parameter | Reference | Moderate exposure | High exposure | p value |
| Glucose [mg/dL (95% CI)] | 84.16 (82.43–85.94) | 95.59 (85.47–95.23) | 84.50 (79.63–89.65) | 0.22a |
| Urea [mg/dL (95% CI)] | 23.99 (22.92–25.11) | 22.25 (21.02–23.54) | 22.29 (20.76–23.94) | 0.03a |
| BUN [mg/dL (95% CI)] | 11.21 (10.71–11.73) | 10.39 (9.82–11.00) | 10.81 (9.83–11.88) | 0.05a |
| Creatinine [mg/dL (95% CI)] | 0.76 (0.73–0.79) | 0.73 (0.70–0.77) | 0.76 (0.71–0.80) | 0.09a |
| Uric acid [mg/dL (± SD)] | 5.32 (1.31) | 5.80 (1.66) | 5.97 (1.77) | 0.02b |
| Cholesterol [mg/dL (± SD)] | 182.62 (39.25) | 200.23 (37.64) | 182.59 (35.68) | < 0.001b |
| GOT [UI/L (± SD)] | 24.42 (20.96) | 30.99 (32.25) | 23.54 (12.11) | < 0.01b |
| GPT [UI/L (95% CI)] | 21.09 (18.96–23.47) | 30.17 (26.42–34.44) | 25.11 (21.58–29.22) | < 0.001a |
| GGT [UI/L (95% CI)] | 26.04 (23.17–29.25) | 40.11 (34.85–46.16) | 32.73 (26.90–39.82) | < 0.001a |
| Albumin [g/dL (95% CI)] | 4.70 (4.65–4.75) | 4.75 (4.69–4.81) | 4.77 (4.69–4.85) | 0.06a |
| Globulin [g/dL(± SD)] | 2.72 (0.33) | 2.83 (0.34) | 2.83 (0.43) | 0.04b |
| Hemoglobin [g/dL (± SD)] | 15.06 (1.41) | 14.79 (1.48) | 14.80 (1.40) | 0.27b |
| Hematocrit [%(± SD)] | 44.50 (3.83) | 44.65 (3.91) | 44.83 (3.36) | 0.84b |
| Leukocytes [/mm3 (± SD)] | 6702.31 (1592.33) | 7769.01 (1775.91) | 8187.33 (2219.47) | < 0.001b |
| Neutrophils [/mm3 (95% CI)] | 3471.52 (3241.85–3717.46) | 4097.15 (3868.08–4339.78) | 4284.46 (3815.55–4810.98) | < 0.001a |
| Eosinophils [/mm3 (95% CI)] | 258.00 (218.52–304.61) | 309.71 (265.18–361.73) | 293.72 (235.54–366.27) | 0.17a |
| Basophils [/mm3 (95% CI)] | 67.59 (61.08–74.81) | 73.53 (63.49–85.17) | 99.94 (80.30–124.39) | < 0.01a |
| Lymphocytes [/mm3 (95% CI)] | 2216.34 (2115.63–2321.85) | 2470.69 (2333.91–2615.48) | 2393.40 (2192.15–2613.13) | < 0.01a |
| Monocytes [/mm3 (± SD)] | 326.12 (173.78) | 468.49 (186.97) | 224.34 (244.34) | < 0.001b |
| Platelets [/mm3 (± SD)] | 264,644.6 (61,745.16) | 258,289.3 (63,096.15) | 254,916.7 (65,862.8) | 0.56b |
BUN, blood urea nitrogen; GOT, glutamic oxalacetic transaminase; GPT, glutamic pyruvic transaminase; GGT, gamma-glutamyl transferase
ap values were obtained by Kruskal − Wallis and post hoc Dunn’s test
bp values were obtained by ANOVA, with post hoc Bonferroni test
95% CI, 95% confidence interval; ± SD, ± standard deviation