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. 2022 Sep 30;13:990623. doi: 10.3389/fgene.2022.990623

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Copyright © 2022 Ma, Yang, Ji and Wen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Biological characteristics, pathways, and immune-related analyses between high- and low-risk groups. (A,B) Heatmaps of GSVA between the different risk groups with C2 and hallmark gene sets. (C) Boxplots illustrating expression of immune checkpoints of the high- and low-risk groups. (D) Boxplots illustrating abundance of immune cells in the high- and low-risk groups. Red boxes: high-risk group; blue boxes: low-risk group. (*: p < 0.05, **: p < 0.01, and ***: p < 0.001). (E) High-risk group had higher TMB than the low-risk group (p = 1e-11).