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. 2022 Oct 13;12:17194. doi: 10.1038/s41598-022-22154-8

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Anti-CSP mAb reactivity to whole SPZ lysate. (a) ELISA curve of anti-CSP mAbs binding at different concentrations to whole SPZ lysate to determine mAb affinity (expressed as K_D). (b) ELISA curve of the effect of a serial dilution of ammonium thiocyanate on anti-CSP mAbs binding to whole SPZ lysate to determine mAb avidity (expressed as IC_50A).