Figure 2.

High congruence of male and female AD portraits. RRHO heat map¹¹¹ is shown for comparisons of the male AD portrait (Y axis) and the female AD portait (X axis). Color is − log transformed hypergeometric p value showing the strength of the overlap as positive or negative enrichment. There is a high level of similarity in downregulated genes in both male and female AD datasets (red in upper right quadrant; see arrow) and in upregulated genes in both datasets (red in lower left hand quadrant; see arrow). All genes are used in RRHO analysis and upregulated genes are shown in red and downregulated genes shown in blue in the axis for each comparison.