TABLE 4.
Relationship between TRIMs and chemoresistance.
| Name | Type of cancer | Mechanism | Effect on tumor chemoresistance | Reference |
|---|---|---|---|---|
| TRIM7 | Osteosarcoma | Promote the ubiquitination of breast cancer metastasis inhibitor 1 (BRMS1) | Promote | ADDIN NE.Ref.{43C88769-6577-4C85-8A7A-6B9D4BCE28A6}(Zhou et al., 2020) |
| TRIM65 | NSCLC | Promoting cisplatin resistance in A549/DDP cells by regulating Mir-138-5p /ATG7. | Promote | ADDIN NE.Ref.{08E35499-6045-412E-A4B2-1DC1A939C640}(Pan et al., 2019) |
| TRIM11 | NPC | Activation of the β-catenin/ABCC9 axis by P62 selective autophagic degradation of Daple. | Promote | ADDIN NE.Ref.{E8D3D269-3174-402B-A24E-1F9695D79B21}(Zhang et al., 2020) |
| TRIM58 | Breast cancer | Inactivation of p53/p21 by DDX3 ubiquitination in breast cancer. | Promote | ADDIN NE.Ref.{7069FE60-D253-402B-BF16-249CB7747503}(Wang et al., 2022) |
| TRIM46 | Lung cancer | AKT/HK2 signaling is activated by modifying PHLPP2 ubiquitination. | Promote | ADDIN NE.Ref.{8D9460F1-5A44-43D8-878E-45D31E1EFEE8}(Tantai et al., 2022) |