Skip to main content
. 2022 Sep 30;13:999380. doi: 10.3389/fphar.2022.999380

TABLE 4.

Relationship between TRIMs and chemoresistance.

Name Type of cancer Mechanism Effect on tumor chemoresistance Reference
TRIM7 Osteosarcoma Promote the ubiquitination of breast cancer metastasis inhibitor 1 (BRMS1) Promote ADDIN NE.Ref.{43C88769-6577-4C85-8A7A-6B9D4BCE28A6}(Zhou et al., 2020)
TRIM65 NSCLC Promoting cisplatin resistance in A549/DDP cells by regulating Mir-138-5p /ATG7. Promote ADDIN NE.Ref.{08E35499-6045-412E-A4B2-1DC1A939C640}(Pan et al., 2019)
TRIM11 NPC Activation of the β-catenin/ABCC9 axis by P62 selective autophagic degradation of Daple. Promote ADDIN NE.Ref.{E8D3D269-3174-402B-A24E-1F9695D79B21}(Zhang et al., 2020)
TRIM58 Breast cancer Inactivation of p53/p21 by DDX3 ubiquitination in breast cancer. Promote ADDIN NE.Ref.{7069FE60-D253-402B-BF16-249CB7747503}(Wang et al., 2022)
TRIM46 Lung cancer AKT/HK2 signaling is activated by modifying PHLPP2 ubiquitination. Promote ADDIN NE.Ref.{8D9460F1-5A44-43D8-878E-45D31E1EFEE8}(Tantai et al., 2022)