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The inhibition effect of BR102 on TGF-β signaling pathway. (A) BR102 blocked the interaction of TGF-β1 with TGF-βRII. (B) BR102 inhibited TGF-β1-induced SMAD signaling in a TGF-β/SMAD luciferase reporter gene assay. (C) BR102 reversed TGF-β1 induced proliferation inhibition of TF-1 cells.
