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. 2022 Sep 22;14(19):4604. doi: 10.3390/cancers14194604

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Planning workflow. Workflow of the DPBN planning. The QF-based discretization method was used to identify the target dose levels (DPBC map). Moreover, the treatment planning system (TPS) structured-based dose optimization (TDD map) was conducted. The deliverable optimized dose maps (TDD map) were compared with the DPBN maps and evaluated in terms of QF dose index (QF evaluation). Finally, a delivery quality assurance (Delivery QA) of the plans was carried out and ranked in terms of γ-index.