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. 2022 Oct 13;9(6):e200035. doi: 10.1212/NXI.0000000000200035

Figure 1. MOG-IgG–Positive Pediatric Patients With Clinical Presentation at the First Event and After at Least 24 Months.

Figure 1

116/155 MOG-IgG–positive pediatric patients were included in the study. Fifty-nine patients presented with ADEM, 21 patients with unilateral ON, 16 patients with bilateral ON, 6 patients with myelitis, 8 patients with NMOSD, and 6 patients with encephalitis. After at least 24 months of a clinical follow-up, further relapses have occurred in 24 patients with ADEM, 12 patients with unilateral ON, 2 patients with bilateral ON, 1 patient with myelitis, 2 patients with NMOSD, and 3 patients with encephalitis. Thirty-nine/155 patients had to be excluded because of the following reasons: no available serum sample from disease onset (n = 7), insufficient clinical (n = 2) or serologic (n = 26) follow-up data, or a final diagnosis of MS (n = 4). ADEM = acute disseminated encephalomyelitis; IgG = immunoglobulin G; MOG = myelin oligodendrocyte glycoprotein; NMOSD = neuromyelitis optica spectrum disorder; ON = optic neuritis.