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. Author manuscript; available in PMC: 2022 Oct 14.
Published in final edited form as: J Alzheimers Dis. 2022;89(1):193–207. doi: 10.3233/JAD-220399

Table 2:

Pearson’s correlation coefficient of proteins measured by SOMAscan and immunoassay platforms.

Analyte Soma ID Correlation Coefficient R-Squared P-value Slope
NfL 10082–251 0.91 0.84 3.71 ×10−148 0.72
Neurogranin 18303–39 0.93 0.86 <10−150 0.92
SNAP-25 13105–7 0.06 0.004 0.34 0.06
sTREM2 11851–21 0.66 0.44 5.15 ×10−140 0.64
16300–4 0.65 0.43 6.91 ×10−138 0.61
5635–66 0.64 0.41 1.76 ×10−129 0.63
VILIP-1 13522–20 0.91 0.82 5.28 ×10−89 0.86
20197–14 0.92 0.85 2.07 ×10−98 0.85

Standard scores were used to calculate the correlation coefficient. Significance was determined based on a p-value threshold of 0.05. Slope corresponds to a regression line fitted using immunoassay score as independent variable and SOMA score as dependent variable. Samples from all available cohorts were used for correlation calculation.