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. 2022 Sep 30;14(19):4794. doi: 10.3390/cancers14194794

Figure 6.

Figure 6

Graphical schematic summarizes the regulation of ORAI1-mediated Ca2+ influx by AKT. Increased AKT phosphorylation as a result of either PTEN silencing or pharmacological activation with SC79, results in increased Ca2+ influx through ORAI1 channels.