Figure 2.

Effect of viable lactic acid bacteria strains on the expression of interferon and interferon-induced antiviral genes in porcine alveolar macrophages after the activation of Toll-like receptor 3 (TLR3). Alveolar macrophages were stimulated with viable bacteria and then challenged with the TLR3 agonist poly(I:C). The expression of IFN-β and RNAseL were analyzed by qPCR after 12 h of TLR3 activation. Non-bacteria treated alveolar macrophages challenged with poly(I:C) were used as controls. The results represent data from three independent experiments. Significant differences were observed when compared to poly(I:C)-challenged control porcine alveolar macrophages. * (p < 0.05). Correlation between the fold expression of IFN-β and RNAseL by a linear regression function was performed.