|
Modifiable risk factors
|
Exposure to UV radiation (e.g., sunlight or use of tanning devices) |
| History of blistering sunburns at a young age |
| Medications (e.g., psoralen or immunosuppressive drugs) |
| Environmental exposure to chemicals (e.g., heavy metals or pesticides) |
|
Non-modifiable risk factors
|
Age |
| Sex |
| Ethnicity |
| Individual phenotypic characteristics (e.g., skin and light eyes, red or blond hair and high density of freckles) |
| Clinical characteristics of the patient (e.g., increased number of common nevi or presence of atypical nevi) |
| Personal and family history of skin cancers |
| Personal history of diseases that compromise the immune system (e.g., hematologic malignancies or infection by HIV) |
| Genetic alterations |
| Specific genetic conditions (e.g., albinism or xeroderma pigmentosum) |
