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. 2022 Jul 9;8(5):1218–1248. doi: 10.1002/cre2.617

Table 4.

In vitro studies related to the treatment of cracked teeth

Study Specimens Method Restorations Outcomes
Studies relevant to teeth with normal pulp or reversible pulpitis (n =3)
Kim et al. (2021) Three‐dimensional cracked tooth models Finite element analysis Direct/indirect composite, ceramic inlays/onlays, gold crown with/without resin core Ceramic inlays/onlays and gold crown with resin core showed the most favorable stress distribution
Magne et al. (2012) Extracted human third molars with standardized MOD+ cavities and simulated cracks Cyclic fatigue test Indirect composite inlays/onlays with/without fiber patch Significantly higher fatigue resistance of onlays compared to inlays; no effect of fiber patch
Naka et al. (2018) Extracted human third molars with standardized MOD+ cavities and simulated cracks Cyclic fatigue test Direct/indirect composite with/without cuspal coverage Significantly higher fatigue resistance of direct groups compared to indirect; no significant effect of cuspal coverage
Studies relevant to endodontically treated teeth (n  = 3)
Anton Y. Otero et al. (2021) Extracted human third molars with simulated cracks and endodontic treatment Cyclic fatigue test CAD/CAM± resin composite endocrowns with/without fiber‐reinforced composite base A fiber‐reinforced base did not significantly affect the fracture resistance of teeth restored with endocrowns, but it resulted in more fractures being restorable (50‐80%) in comparison to the control group (30%)
Lin et al. (2013) Three‐dimensional finite element premolar models with different crack depths Finite element analysis CAD/CAM± ceramic crowns or onlays or endocrowns Onlays exhibited higher failure probabilities compared to both crowns and endocrowns; endocrowns provided comparable fracture resistance to crowns in cases of shallow cracks (about 1 mm above bone level), but they showed higher failure risk for deep cracks (below bone level to mid‐root)
Shi et al. (2021) Three‐dimensional finite element models with simulated cracks and endodontic treatment Finite element analysis and fracture failure test Crowns and onlays with/without different types of fiber reinforcement Crowns resulted in superior fracture resistance than onlays when both combined with an annular fiber‐reinforced base; fiber‐reinforced onlays exhibited significantly more favorable fracture pattern compared to crowns