TABLE 1.
Statistical comparisons for the groups of HI antibody titers and AUCs for the four outcome measuresa
Group | Log HI antibody titer
|
AUC for:
|
||||
---|---|---|---|---|---|---|
Preexposure | Postexposure | Log IL-6 concn (pg/ml) | Nasal secretion wt (g) | Nasal symptom score | Systemic symptom score | |
Subjects who did not shed virus (n = 5) | 1.5 ± 0.4 | 1.6 ± 0.3 | 0.9 ± 1.2 | 1.9 ± 2.6 | 6.6 ± 6.8 | 4.2 ± 5.3 |
Subjects who shed virus (n = 12) | 0.7 ± 0.2 (<0.01) | 1.6 ± 0.2 (NSb) | 2.2 ± 0.5 (<0.05) | 32.5 ± 23.6 (<0.01) | 15.3 ± 8.1 (<0.05) | 11.3 ± 8.4 (<0.06) |
Data are means ± standard deviations. P values, in parentheses, are versus the data for the subjects who did not shed virus.
NS, not significant.