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. 2022 Sep 30;13:987401. doi: 10.3389/fendo.2022.987401

Table 1.

MR Results of Hypothyroidism on Risk of HCC.

Exposure Method No. of SNPs OR (95% CI) P P-het P-intercept P-global
MR-Egger 71 0.994 (0.988, 0.999) 0.045 0.673 0.283
Weighted median 71 0.996 (0.992, 1.000) 0.069
Hypothyroidism IVW 71 0.997 (0.994, 0.999) 0.016 0.666
Simple mode 71 0.994 (0.985, 1.002) 0.181
Weighted mode 71 0.995 (0.990, 1.000) 0.115
MR-PRESSO (raw) 71 0.997 (0.994-0.999) 0.020 0.669

HCC, Hepatocellular carcinoma; IVW, inverse variance weighted; MR, Mendelian randomization; OR, odds ratio; P-het, P value for heterogeneity using Cochran Q test; P-intercept, P value for MR-Egger intercept; SNP, single-nucleotide polymorphism.