Table 1.
MR Results of Hypothyroidism on Risk of HCC.
| Exposure | Method | No. of SNPs | OR (95% CI) | P | P-het | P-intercept | P-global |
|---|---|---|---|---|---|---|---|
| MR-Egger | 71 | 0.994 (0.988, 0.999) | 0.045 | 0.673 | 0.283 | ||
| Weighted median | 71 | 0.996 (0.992, 1.000) | 0.069 | ||||
| Hypothyroidism | IVW | 71 | 0.997 (0.994, 0.999) | 0.016 | 0.666 | ||
| Simple mode | 71 | 0.994 (0.985, 1.002) | 0.181 | ||||
| Weighted mode | 71 | 0.995 (0.990, 1.000) | 0.115 | ||||
| MR-PRESSO (raw) | 71 | 0.997 (0.994-0.999) | 0.020 | 0.669 |
HCC, Hepatocellular carcinoma; IVW, inverse variance weighted; MR, Mendelian randomization; OR, odds ratio; P-het, P value for heterogeneity using Cochran Q test; P-intercept, P value for MR-Egger intercept; SNP, single-nucleotide polymorphism.