Table 2. Summary of performance characteristics of biomarkers in cirrhotic patients (according to Jothimani et al. (69)).

Biomarker	NPV, %	PPV, %	Sensitivity, %	Specificity, %	95% CI	Cut-off
CG	98	98	97	96	NA	NA
HA	93	98	96	97	NA	NA
CIV	87	98	92	97	NA	NA
PIIIP N-P	86	98	92	96	NA	NA
LN	78	95	87	96	NA	NA
95% CI for any of the characteristics (NPV; PPV; specificity; sensitivity). Since 95% CI values are not available, no reliable conclusions could be obtained and the given biomarkers results are only indications. NPV - negative predictive value. PPV - positive predictive value. 95% CI - 95% confidence interval. NA - not available. CG - cholylglycine. HA - hyaluronic acid. CIV - type IV Collagen. PIIIP N-P - collagen type III N-peptide. LN - laminin.