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. 2022 Aug 3;23(11):1701–1718. doi: 10.1111/mpp.13252

TABLE 3.

Summary of studies that have employed CRISPR/Cas9 strategies for the targeting of host susceptibility genes

Plant species Name of the susceptibility (S) gene targeted Virus name Reference
Arabidopsis thaliana AteIF(iso)4E Turnip mosaic virus (TMV) Pyott et al. (2016)
eIF4E1 Clover yellow vein virus (CYVV) Bastet et al. (2019)
Hordeum vulgare (barley) eIF4E1 Barley mild mosaic virus (BaMMV) Hoffie et al. (2021)
Manihot esculenta (cassava) nCBP‐1/2 Cassava brown streak virus (CBSV) Gomez et al. (2019)
Cucumis sativus (cucumber) CseIF4E

Zucchini yellow mosaic virus (ZYMV)

Cucumber vein yellowing virus (CVYV)

Papaya ring spot mosaic virus‐W (PRSV‐W)

Chandrasekaran et al. (2016)
Nicotiana benthamiana CLC‐Nb1a/b Potato virus Y (PVY) Sun et al. (2018)
Oryza sativa (rice) OseIF4G Rice tungro spherical virus (RTSV) Macovei et al. (2018)
Solanum tuberosum (potato) Coilin Potato virus Y (PVY) Makhotenko et al. (2019)
Glycine max (soybean) GmF3H1/2, FNSII‐1 Soybean mosaic virus (SMV) Zhang et al. (2020)
Solanum lycopersicum (tomato) TOM1 Tomato brown rugose fruit virus (ToBRFV) Ishikawa et al. (2022)
eIF4E1 Pepper mottle virus (PepMoV) Yoon et al. (2020)
eIF4E1

Cucumber mosaic virus (CMV)

Potato virus Y (PVY)

Atarashi et al. (2020)
eIF4E1 Pepper veinal mottle virus (PVMV) Kuroiwa et al. (2022)
SleIF4E1, SleIF4E2 Potato virus Y (PVY) Kumar et al. (2022)
Triticum aestivum (wheat) TaPDIL5‐1 Wheat yellow mosaic virus (WYMV) Kan et al. (2022)