Table 1.
Study characteristics of included studies.
| Study | Patient number | Indication | LBB captured n (%) | Paced QRS duration (ms) | Stim-LVAT (ms) | ||||
|---|---|---|---|---|---|---|---|---|---|
| LBBP | LVSP | P | LBBP | LVSP | P | ||||
| Qian et al. (7) | 68 | Bradycardia | 47 (69%) | 113.4 ± 9.8 | 120.7 ± 10.7 | 0.005 | None | None | None |
| Zhang et al. (8) | 106 | Bradycardia | 78 (74%) | 115.0 ± 9.4 | 126.6 ± 12.5 | <0.01 | 70.8 ± 5.7 | 83.3 ± 7.8 | <0.01 |
| Jastrzebski et al. (6) | 468 | Bradycardia and/or HF | 124 (26%) | 154.5 ± 21.2 (NSLBBP) | 159.3 ± 20.2 | None | 74.7 ± 12.0 (NSLBBP) | None | None |
| 175.8 ± 26.5 (SLBBP) | 74.4 ± 13.0 (SLBBP) | ||||||||
| Heckman et al. (5) | 50 | Bradycardia, AVN ablate | 31 (62%) | 123 ± 22 | None | None | 73 ± 15 | 81 ± 13 | 0.138 |
| Wu et al. (3) | None | Bradycardia and/or HF with LBBB | 30 (21 of non-LBBB; 9 of LBBB) | 134.3 ± 14.9 (non-LBBB) | 141.7 ± 16.6 | 0.003 | 70.7 ± 7.7 | 90.8 ± 15.2 | <0.001 |
| 138.4 ± 15.4 (LBBB) | 144.7 ± 14.0 | 0.027 | 81.7 ± 8.4 | 97.4 ± 13.1 | <0.001 | ||||
| Curila et al. (12) | 68 | Bradycardia | None | 104 (100, 108) | 103 (100, 107) | >0.05 | 70 (66, 73) | 86 (84,89) | <0.01 |
| Curila et al. (13) | 96 | Bradycardia | 57 (59%) | LBBP <LVSP (non-quantitative) | <0.001 | 68 (65, 71) (NSLBBP) | 86 (83, 89) | <0.001 | |
| 70 (67, 73) (SLBBP) | |||||||||
| Vijayaraman et al. (14) | 32 | LBBB | 25 (78%) | 141 ± 15 | None | None | 75.2 ± 8.8 (NSLBBP) | 90.4 ± 9.1 | <0.001 |
| 76.9 ± 8.3 (SLBBP) | |||||||||
| Jastrzebski et al. (9) | 468 | Bradycardia and/or HF | 124 (26%) | 154.5 ± 21.2 (NSLBBP) | 159.3 ± 20.2 | None | 78.4 ± 10.8 (NSLBBP) | 98.4 ± 13.9 | None |
| 144.5 ± 24.4 (SLBBP) | |||||||||
| Shimeno et al. (10) | 51 | Bradycardia without LBBB | 21 (41%) | 137 ± 9 (NSLBBP) | 135 ± 7 | >0.05 | 60 ± 4 (NSLBBP) | 76 ± 7 | <0.01 |
| 154 ± 11 (SLBBP) | 60 ± 4 (SLBBP) | ||||||||
| Chen et al. (4) | 43 | Bradycardia without LBBB | 27 (63%) | 135.6 ± 10.9 | 141.6 ± 13.6 | 0.118 | 65.8 ± 8.1 | 81.6 ± 7.3 | <0.001 |
| Peng et al. (15) | 59 | Bradycardia | 46 (78%) | 105.3 ± 15.6 | 109.2 ± 9.6 | 0.287 | 72.0 ± 10.0 | 86.4 ± 12.3 | 0.001 |
| Zhou et al. (16) | 46 | Bradycardia and/ or HF | 23 (50%) | 104.26 ± 19.00 | 118.09 ± 23.20 | 0.032 | 48.70 ± 13.67 | 58.70 ± 13.67 | 0.032 |
| Shimeno et al. (11) | 126 | Bradycardia | 52 (41%) | 135 ± 16 (NSLBBP) | 141 ± 16 | None | 62 ± 9 | 72 ± 10 | <0.001 |
| 150 ± 22 (SLBBP) | |||||||||
| Qian et al. (17) | 118 | Bradycardia and/or HF ± LBBB | 90 (76%) | 115.9 ± 20.3 (Bradycardia) | 135.3 ± 21.0 | 0.004 | 67.8 ± 7.8 | 80.9 ± 10.4 | <0.001 |
| 136.0 ± 14.4 (HF ± LBBB) | 152.2 ± 15.9 | 0.005 | 77.1 ± 8.8 | 94.6 ± 10.4 | <0.001 | ||||
LBB, left bundle branch; Stim-LVAT, stimulus artifact to left ventricular activation time in lead V5 or V6; LBBP, left bundle branch pacing; NSLBBP, non-selective LBBP; SLBBP, selective LBBP; LVSP, left ventricular septal pacing; AVN, atrioventricular node; HF, heart failure; LBBB, left bundle branch pacing.