Figure 9.
TFAP2C knockdown alone or combined with cisplatin inhibits BCa cell growth in vivo. (A) Images of tumors in nude mice after different treatments. Arrows indicate the subcutaneous tumors. (B) Morphology of the subcutaneously implanted tumor. (C) Tumor weight. (D) Volume of tumor at each time point. (E) Representative images of TUNEL staining and IHC staining for Bax and vimentin in the cisplatin alone and cisplatin combined with TFAP2C knockdown groups. Scale bars, 20 μm. (F–H) Expression levels of major proteins in different groups. Data represent the mean ± standard deviation (SD) of three independent experiments (* p < 0.05, ** p < 0.01, *** p < 0.001, ns, not significant).
