Table 3.

The Diagnostic Values of Hepatic Biochemical Tests for the Diagnosis of PE Among Pregnant Women Attending at the University of Gondar Comprehensive Specialized Hospital ANC Unit from February to May 2021 (n = 126)

LFT Measurements	AUC (95% CI)	Cut-Off Point	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)	Accuracy (%)	Youden Index
AST (U/l)	0.89 (0.84–0.95)	≥58.50	74.6	87.3	85.5	77.5	80.9	0.619
ALT (U/l)	0.78 (0.70–0.86)	≥45.50	61.9	81.0	76.5	68.0	71.4	0.429
Total bilirubin (mg/dl)	0.69 (0.60–0.79)	≥1.14	42.9	93.7	87.1	62.1	68.3	0.365

Note: P-value by independent t-test.

Abbreviations: PE, Preeclampsia; NT, Normotensive; AST, Aspartate aminotransferase; ALT, Alanine aminotransferase; AUC, Area under the curve; PPV, positive predictive value; NPV, negative predictive value.