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. 2022 Sep 30;12:961394. doi: 10.3389/fonc.2022.961394

Table 1.

Baseline characteristics of the two groups before and after PSM.

Variable Before PSM After PSM
Grading TACE-A(n=148) TACE-AP(n=68) P value SMD TACE-A(n=59) TACE-AP(n=59) P value SMD
Gender Male 126 (85.1) 62 (91.2) 0.313 0.188 54 (91.5) 53 (89.8) 1.000 0.058
Female 22 (14.9) 6 (8.8) 5 (8.5) 6 (10.2)
Age ≤60 98 (66.2) 49 (72.1) 0.485 0.127 43 (72.9) 41 (69.5) 0.839 0.075
>60 50 (33.8) 19 (27.9) 16 (27.1) 18 (30.5)
Child-Pugh classification A 130 (87.8) 65 (95.6) 0.124 0.284 57 (96.6) 56 (94.9) 1.000 0.084
B 18 (12.2) 3 (4.4) 2 (3.4) 3 (5.1)
PVTT None 79 (53.4) 28 (41.2) 0.208 0.260 27 (45.8) 27 (45.8) 0.857 0.103
Type I+II 50 (33.8) 31 (45.6) 22 (37.3) 24 (40.7)
Type III 19 (12.8) 9 (13.2) 10 (16.9) 8 (13.6)
Metastasis None 90 (60.8) 35 (51.5) 0.253 0.189 34 (57.6) 32 (54.2) 0.853 0.068
Have 58 (39.2) 33 (48.5) 25 (42.4) 27 (45.8)
AFP(ng/mL) <400 87 (58.8) 42 (61.8) 0.791 0.061 32 (54.2) 35 (59.3) 0.710 0.103
≥400 61 (41.2) 26 (38.2) 27 (45.8) 24 (40.7)
HBV None 47 (31.8) 29 (42.6) 0.161 0.277 22 (37.3) 22 (37.3) 1.000 <0.001
Have 101 (68.2) 39 (57.4) 37 (62.7) 37 (62.7)
ECOG Score 0 21 (14.2) 13 (19.1) 0. 470 0.133 12 (20.3) 12 (20.3) 1.000 <0.001
1 127 (85.8) 55 (80.9) 47 (79.7) 47 (79.7)
TBIL (g/L,mean±SD) 21.92±10.31 21.11±8.44 0.574 0.186 20.65±8.42 20.76±8.50 0.947 0.012
AlB (μmol/L,mean±SD) 37.25±4.91 38.01±6.90 0.358 0.126 38.11±4.56 37.72±7.12 0.729 0.064
ALT (U/L,mean±SD) 46.55±66.25 37.94±20.51 0.296 0.176 37.24±20.55 37.80±21.61 0.886 0.027
Cr (umol/L,mean±SD) 58.77±11.90 61.69±15.08 0.126 0.215 58.54±11.25 59.31±11.15 0.710 0.069
Number of liver tumors 1 25 (16.9) 17 (25.0) 0.373 0.201 11 (18.6) 11 (18.6) 1.000 <0.001
2 76 (51.4) 31 (45.6) 28 (47.5) 28 (47.5)
≥3 47 (31.8) 20 (29.4) 20 (33.9) 20 (33.9)
Maximum tumor diameter (mm,mean±SD) 77.08±45.79 70.09±37.57 0.272 0.167 69.41±44.64 68.48±37.66 0.903 0.023
Number of TACE 1.95 (1.16) 2.12 (1.52) 0.362 0.127 1.90 (1.12) 2.14 (1.54) 0.340 0.176

ECOG, Eastern Cooperative Oncology Group; AFP, alpha-fetoprotein; TBIL, total bilirubin; ALB, albumin; ALT, alanine aminotransferase; Cr, creatinine.