Table 2.
Gene clusters found significantly enriched in either S. capitis ssp. capitis or ssp. ureolyticus (p < 0.001).
| Gene name | S. capitis reference | Annotation | S. capitis ssp. capitis (%) | S. capitis ssp. ureolyticus (%) |
|---|---|---|---|---|
| group_2869 | Hypothetical protein | 100 | 0 | |
| group_459 | Putative phage head morphogenesis protein | 100 | 0 | |
| crtNX | Dehydrosqualene desaturase | 100 | 4.76 | |
| hdcA | Histidine decarboxylase proenzyme | 100 | 6.67 | |
| hsdM | Type I restriction-modification system methyltransferase subunit | 100 | 21.90 | |
| group_1023 | Putative transcriptional regulator | 100 | 29.52 | |
| group_2665 | AYP1020_RS09385 | Putative protein YjdF | 100 | 34.29 |
| sasCX | Cell-wall-anchored protein SasC | 100 | 35.24 | |
| arcAX | Arginine deiminase | 98.72 | 6.67 | |
| arcCX | Carbamate kinase ArcC1 | 98.72 | 7.62 | |
| arcDX | Arginine/ornithine APC family amino acid-polyamine-organocation transporter antiporter | 98.72 | 7.62 | |
| argFX | Ornithine carbamoyltransferase | 98.72 | 7.62 | |
| hsdSX | Type I restriction modification DNA specificity protein;type I restriction modification system site specificity determination subunit HsdS_1 | 98.72 | 7.62 | |
| trkG | Trk family potassium (K+) transporter ABC protein | 98.72 | 11.43 | |
| arsB | Arsenical pump membrane protein | 98.72 | 16.19 | |
| cdr | Coenzyme A disulfide reductase | 98.72 | 19.05 | |
| arsR | Arsenical resistance operon repressor | 98.72 | 19.05 | |
| group_2407 | Arsenate reductase (glutaredoxin) | 98.72 | 20.95 | |
| arsA | Arsenical pump-driving ATPase | 98.72 | 55.24 | |
| arsD | Arsenical resistance operon trans-acting repressor ArsD | 92.31 | 37.14 | |
| pyrBX | Aspartate carbamoyl transferase catalytic subunit | 98.72 | 0.95 | |
| group_1353 | AYP1020_RS02690 | Hypothetical protein | 0 | 100 |
| group_798 | AYP1020_RS11575 | Hypothetical protein | 0 | 100 |
| group_1413 | AYP1020_RS11570 | Hypothetical protein | 0 | 99.05 |
| icaCX | AYP1020_RS08445 | Putative poly-beta-16-N-acetyl-D-glucosamine export protein | 0 | 98.10 |
| fmrO | AYP1020_RS12300 | rRNA methyltransferase FmrO; hypothetical protein | 35.90 | 96.19 |
| dapF | AYP1020_RS09635 | Diaminopimelate epimerase | 35.90 | 96.19 |
| qorB | AYP1020_RS06480 | Cobalt (Co2+) ABC superfamily ATP binding cassette transporter membrane protein | 0 | 78.10 |
| group_1472 | Antibacterial protein (phenol soluble modulin) | 0 | 55.24 | |
| mqo | Putative malate: quinone oxidoreductase 2 | 0 | 64.76 | |
| pfpI | Intracellular protease | 0 | 60 | |
| opp1B | Oligopeptide ABC superfamily ATP binding cassette transporter membrane protein | 35.90 | 84.76 | |
| opp1D | Oligopeptide ABC superfamily ATP binding cassette transporter ABC protein | 35.90 | 84.76 | |
| group_687 | Hypothetical protein | 35.90 | 84.76 | |
| group_585 | MFS family major facilitator transporter | 35.90 | 84.76 | |
| opp1A | Oligopeptide ABC superfamily ATP binding cassette transporter binding protein | 35.90 | 84.76 | |
| opp1C | Oligopeptide ABC superfamily ATP binding cassette transporter membrane protein | 35.90 | 84.76 | |
| opp1F | ABC superfamily ATP binding cassette transporter ABC protein | 35.90 | 84.76 | |
| blaRX | β-lactamase regulatory protein | 6.41 | 62.86 |
Gene clusters, presence and absence, and functional descriptions were obtained from Panaroo and Scoary pangenome analysis of assembled genomes. X these genes exist in different conserved versions in isolates. S. capitis reference gene numbers are from S. capitis AYP1020 (Genbank Assembly Accession: GCA_001028645.1) (Cameron et al., 2015). The complete list can be found at Supplementary Table 2.